1223403-58-4 larotrectinib

Egenskaber

Udseende Gul fast stof
Densitet 1,55 ± 0. 1 g/cm3
Opbevaringstemp. Rt
Opløselighed opløselig i DMSO (op til 5 mg/ml).
PKA8.41 ± 0. 40
 

Anvendelse:

Larotrectinib er en meget selektiv TRK -hæmmer, der specifikt er rettet mod tumorer med NTRK -genfusion og udviser betydelige inhiberende effekter.

 

Synonymer:

Larotrectinib

1223403-58-4

(S) -n-(5- ((r) -2- (2, 5- difluorophenyl) pyrrolidin -1- yl) pyrazol o [1, 5- a] pyrimidin -3- yl) -3- hydroxypyrrolidin -1- carboxamid

Loxo 101

Vitrakvi

(3s) -n-[5- [(2r) -2- (2, 5- difluorophenyl) pyrrolidin -1- yl] pyrazol o [1, 5- a] pyrimidin -3- yl] -3- hydroxypyrrolidin -1- carboxamid

1- pyrrolidinecarboxamid, N-[5- [(2r) -2- (2, 5- difluorophenyl) -1- pyrrolidinyl] pyrazolo [1, 5- a] pyrimidin {-3- yd (3s)-

Larotrectinib (loxo -101 gratis base)

1- pyrrolidinecarboxamid, N-(5- ((2R) -2- (2, 5- difluorophenyl) -1- pyrrolidinyl) pyrazolo (1, 5- a) pyrimidin {-3-} yl) {{-3- ydoy (3s)-

Larotrectinibum

(3S) -n-(5- ((2r) -2- (2, 5- difluorophenyl) pyrrolidin -1- yl) pyrazol o (1, 5- a) pyrimidin -3- yl) -3- hydroxypyrrolidin -1- carboxamid

Larotrectinib (standard)

Arry -470; Larotrectinib

C21H22F2N6O2

(3S) -n-(5- ((2r) -2- (2, 5- difluorophenyl) pyrrolidin - 1- yl) pyrazol O (1, 5- a) pyrimidin -3- yl) -3- hydroxypyrrolidin - 1- carboxamid

(3S) -n-(5- ((2r) -2- (2, 5- difluorophenyl) pyrrolidin -1- yl) pyrazol o (1, 5- a) pyrimidin -3- yl) -3- hydroxypyrrolidin - 1- carboxamid

(3S) -n-(5- (2- (2, 5- difluorophenyl) pyrrolidin -1- yl) pyrazolo (1, 5- a) pyrimidin -3- yl) -3- hydroxypyrrolidin -1- carboxamid

 

Populære tags: 1223403-58-4 Larotrectinib, Kina 1223403-58-4 Larotrectinib -producenter, leverandører